Hair mesotherapy and drugs used

Mesotherapy is a treatment that potentially reduces the need for hair transplantation.

Mesotherapy techniques applied for hair loss have been developed from mesotherapy itself.

It can be named as approaches such as Mesoplasty or Mezohair. Positive effects on hair growth have been observed in both men and women.

Mesotherapy is neither complementary medicine nor alternative medicine. This application is a technique of classical medicine compared to the intradermal or subcutaneous injection of pharmacological drugs.

Emelia is the approximation of the area where the disease is located and the treatment application area.

Selected drug mixtures are injected into the skin with special needles and special techniques in small doses locally. The dermis or hypodermis becomes the reservoir area where the active matter is slowly released to the place where the active matter needs to reach through microcirculation. It is therefore a regional-local treatment method.

Scalp mesotherapy is a treatment form that can be applied to the scalp for certain periods in order to stop hair loss, increase the quality of existing hair and activate new hair growth.

With special cocktails, especially vitamin supplements are given to the scalp and blood circulation to this area is improved. Increasing the blood supply of hair follicles helps them to be fed and develop more appropriately.

The superiority of this method compared to other classical drug treatments is the local use of drugs in small doses.

Mesotherapy for hair growth uses different nutrients (such as biotin, hyaluronic acid and silica), vasodilators and androgen blockers. Weeks after the first application, it is observed that the hair grows again, after about six months, the spilled areas are revitalized and replaced with normal hair. Continuation of practices at reasonable intervals is required.

Applications Generally in Mesotherapy;

  1. Intraepidermal application
  2. Superficial intradermal application
    • a-No injection (Nappaj – plastering)
    • b-Injection (Dot format, nappaj)
  3. Deep intradermal injection (Point style- PPP 1-4 mm )
  4. It can be done in the form of hypodermal injection (Point style – PPP 4-10 mm).

Drugs Used in Mesotherapy and Their General Properties

The spies used in practice form the basis of scalp mesotherapy. There is no fixed drug treatment in scalp mesotherapy. Elements with different mechanisms of action according to the existing pathology in each patient are given alone or in combinations. General principle; It is to avoid the combination of many spies in the formulations to be applied and to prepare the composition that can be beneficial to the pathology of the disease with the least consideration.

The issues that can be used with mesotherapy can be classified as follows:

  • Local anesthetics: procaine, xylocaine
  • Vascular effects: buflomedil, melilate-rutin, pentoxifylline, gingko biloba, minoxidil paridyl heparin.
  • They are effective in stimulating the hair follicle and repairing the hair: X-ADN, amino acids, organic silicon.
  • Antiandrogen agents: finasteride, dutasteride, herbal extracts.
  • Antiseborrheic-anti-inflammatory effects: zinc, selenium, salicylate.
  • Effective for keratin biosynthesis: biotin, bepanthene, vitamin A, vitamin B cluster (such as pantothenic acid, vitamin B5), amino acids, oligoelements, zinc, copper, magnesium.

Standard ampoules and vials containing these spies are now available. While spies such as minoxidil, finasteride, dutasteride, biotin, x-adn, organic silicon, d-panthenol can be found in their own names, there are also standard products (such as keractive, haircare) that contain different amino acids, vitamins and oligoelements in combination. These can be applied alone or in combinations.

The composition of the injected should not contain alcohol-based solvents that can cause skin necrosis. The composition should be isotonic, pH neutral, hypoallergenic and well tolerated locally. The most valuable point is to make a definitive diagnosis and choose the correct mixture to be injected before starting the treatment.

Effect Systems and Treatment Purpose of Hair Mesotherapy

Cocktails made with these issues affect the dermal papilla level and regulate the production of keratin by stimulating the development and regeneration of the hair.

The vasodilator (vasodilator) ingredients in the cocktail increase the blood supply of the hair follicles by providing a functional microcirculation. Thus, they provide vitality and shine to the hair. They control the mediators released from the border ends.

Considering the 40% presence of blood cells of the immune system (immune system) in the mesoderm space, they try to prevent immune hair loss by affecting the immune unit.

Vitamins and elements in the cocktail prevent hair loss; they regulate oil secretion and reduce dandruff formation; contribute with their antioxidant properties.

As a result, the point reached; is the topical use of drugs in small doses. The risk of side effects is so low that it can be considered insignificant and the treatment is more effective.

Scalp Mesotherapy Indications

  • In male pattern hair loss (androgenetic alopecia)
  • In cases of traction (due to pulling) spills on the forehead
  • In alopecia areata (ringworm)
  • In postpartum spills
  • In diffuse (general) spills seen mostly in women
  • It is applied in some scalp diseases (such as psoriasis, lichen, seborrheic dermatitis).
  • Early treatment is more effective in men.


Those who are pregnant, breastfeeding, have immunological disease, cancer patients, diabetics, and those receiving anticoagulant treatment are not suitable patients.

There are some things to be considered before and after hair mesotherapy is applied.

What Should Be Done Before Mesotherapy?

  • The level of shedding should be determined by clinical examination.
  • Trichogram examination should be done.
  • The patient should be lying down.
  • Before the application, gloves should be worn and the area should be disinfected with an antiseptic solution. Alcohol, ether, chlorhexidine, betadine are preferred for skin disinfection.
  • Analgesic and anti-inflammatory applications should be discontinued 48 hours before.

What Should Be Done After Mesotherapy?

  • It is recommended to clean the skin with 70% ethyl alcohol after the treatment.
  • As a rule, hot showers should be avoided after the session in order not to increase the risk of allergy.
  • To prevent ecchymosis, post-session hemostasis should be done manually or with the patient’s scale.
  • Sessions should not be repeated at very frequent intervals. It may remove the beneficial effects of the previous session.

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