Stem cells are cells that have the ability to renew themselves and turn into different cells. While it provides tissue and organ development in the mother’s womb, it is used with the aim of repair and renewal in the adult period. Stem cell applications have also been added to the skin rejuvenation methods that have increased in recent years. Fat tissue; It is an endocrine organ that has cells with similar potential to bone marrow-derived cells and shines as a stem cell reserve. Stromal cells, including many cells such as mature adipocytes and stem cells, which make up approximately 90% of the tissue volume.
consists of vascular fraction parts.
Stem cells in adipose tissue have become more attractive because they are resistant to the phenomenon called ischemia, stem cells can be obtained in larger sizes compared to other stem cell source tissues, and because it is a tissue that is essentially uncomfortable for the individual in terms of aesthetics. Therefore, in recent periods, especially aesthetic applications; It has started to be used with the aim of treatment in skin rejuvenation, acne scar, wound healing, burn lesions. Actually, aesthetic
It is also used in many areas such as infertility and musculoskeletal diseases.
How Are Stem Cells Obtained From Adipose Tissue?
The isolation system is carried out under anesthesia in the operating room environment, on sterile bases. With the liposuction formula, the adipose tissue obtained from the abdominal region is subjected to a series of processes such as centrifugation and flow cytometry, and a stem cell cocktail is obtained. Stem cell capacity of the resulting cocktail; It is affected by factors such as the age of the individual (decreases as age increases), isolation conditions. The application is performed under anesthesia for the desired areas or for the target.
Let’s Look at the Effect Mechanism, Activity and Results of Stem Cell Application:
In individuals who received stem cell vaccine; It was observed that fibroblast migration increased, an increase in collagen type 1, and melanocyte proliferation in the melanogenesis pathway through interleukin-6 cytokine inhibited proliferation and melanin synthesis. Thus; skin quality and elasticity increase, wrinkles and spots decrease. Therefore, with the stem cell vaccine technique, new vascularization, new collagen and tissue regeneration and adaptation of the skin physiology are achieved. In studies conducted on individuals with hair loss; An increase in hair density and hair shaft was observed.
Stem Cell Application
It is a very attractive application due to the use of non-foreign cells from the individual’s own body. In one-on-one time; Since these cells do not contain structures called HLA-DR, they are not rejected by the body. One session for skin rejuvenation, acne scars, burn scars and hair loss
is an application.
To Whom Is Stem Cell Application Not Applied?
Pregnancy, lactation, cancer patients, Hepatitis B/C patients, active infection in systemic or process areas and individuals with a Body mass index other than 25-27 kg/m2 are not eligible for this application. In the application area; Discontinuous conditions such as redness, edema, nodule and bruising can be observed. In order to prevent infection, it is recommended to apply the process in absolutely sterile and operating room conditions.